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| trefoil factor 1 ： ウィキペディア英語版 |
trefoil factor 1
Trefoil factor 1 is a protein that in humans is encoded by the ''TFF1'' gene〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7031 )〕 (also called ''pS2'' gene).
== Function ==
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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